Why Choose PrenatalSAFE? ADVANTAGES OF THE PRENATALSAFE TESTS
Qualified molecular biologists and geneticists are always available to help our patients interpret the results. PrenatalSafe® uncovers conditions that other tests do not detect, including rare trisomies, segmental chromosomal abnormalities and monogenic disorders (hereditary and de novo).
- PrenatalSafe® has the lowest false negative rate: 0% in published clinical studies.
- PrenatalSafe® distinguishes between maternal and fetal DNA, which helps to avoid false-positive results.
- Of all NIPTs on the market, PrenatalSafe® has the highest published performance.
- PrenatalSafe® can detect chromosomal abnormalities in the low fetal fraction (4%).
- The PrenatalSafe® Test offers a depth of resolution (> 60 million readings) like no other non-invasive prenatal test available to date.
- PrenatalSafe® Test, in a ISO 17025 approved laboratory with more than 20 years of experience in prenatal diagnostics, more than 200,000 genetic tests are performed annually.
- The PrenatalSafe® test is recommended by a large number of gynaecologists worldwide.
- The PrenatalSafe® test is the only NIPT to date that detects both genome-wide chromosomal abnormalities and severe genetic disorders in the fetus in a single test.
- Unlike other NIPTs available on the market, the Prenatalsafe® test offers a free Rh(D) test (RhSafe). (In the case of an Rh(D)-negative mother and Rh(D)-positive father)
- The PrenatalSafe® test is suitable for both singleton and twin pregnancies (including lost twins) as well as pregnancies resulting from IVF techniques, including gamete donation.
- PrenatalSafe® also offers genetic counselling in case of a positive result.
- PrenatalSafe® tests are performed in Italy (Rome or Milan)
SAFE AND RELIABLE
- It is a non-invasive test that poses no risk to either the fetus or the mother. It is a screening test that analyses circulating fetal DNA from 10 weeks of pregnancy.
- The PrenatalSafe ® test has a sensitivity and specificity of over 99% with a very low false positive rate of less than 0.1% of cases.
- PrenatalSafe ® Karyo Plus shows 99.1% of fetal chromosomal aneuploidies present at birth and achieves a detection rate very similar to conventional (96.9%) and molecular (99.8%) fetal karyotypes obtained by invasive prenatal diagnostic techniques.
- Comparison with Invasive Prenatal Diagnosis The PrenatalSafe® 3 and 5 test allows highlighting 71% and 83.1%, respectively, of chromosomal abnormalities found during pregnancy. With the prenatal SAFE® Plus test, the detection rate reaches 86%. The PrenatalSafe® Complete test represents the highest level of research available. The test allows to detect 95.5% of detectable chromosomal abnormalities in pregnancy (Karyo Plus research level), achieving a detection rate very similar to the traditional fetal karyotype (96.9%) obtained by invasive prenatal diagnostic techniques. It also has the ability to identify mutations responsible for serious genetic diseases.
SENSITIVE
The Limit of Detection (LOD) of the test is determined in the 2% fetal fraction (FF). The value of the fetal fraction is always reported in reports.
PRE-TEST AND POST-TEST GENETIC CONSULTANCY
To explain to patients the purpose of the analysis, the results that can be obtained, and what happens after the examination is complete.
SPEEDY PROCEDURE
Thanks to the recent introduction of new high-resolution FAST Technology, results are available in just 3-5 working days after samples arrive at the lab.
RHSAFE® TEST
Non-invasive prenatal examination that allows to determine the fetal Rh (D) factor. The RhSafe® test is optional and is done free of charge (on request) in Rh(D) negative pregnant women.
FREE TRACKING OF PATHOLOGICAL RESULTS
In cases of positive pathological results with the presence of aneuploidies, structural chromosomal anomalies or genetic mutations, free follow-up is offered by Eurofins Genoma to the referring gynecologists.
SAMPLE COLLECTION AND TRANSPORTION KIT
Certification according to UN3373 and free shipping of biological samples to our laboratories
ALL INCLUSIVE CUSTOMER SUPPORT
Information on sample collection and storage methods, from sample shipping to reporting.
EXCLUSIVE AND SCIENTIFIC SUPPORT